Amace 100mg is a brand of aceclofenac. Its a product of Amtech Med. It belongs to the Non-steroidal anti-inflammatory drugs (NSAIDs) family. It comes in use in a variety of inflammatory conditions.

1. Introduction to Amace100mg

All aceclofenacs, including Amace 200mg100mg are painkillers.  It alleviates pain and symptoms occurring in a variety of conditions. These will be in the list that follows.  

It should be taken as per your doctor’s prescription. Normally, the dose is twice daily, usually after food. Consuming this drug at other times may lead to mild stomach upset. 

You may also like to learn PPIs that curb down the side effect of NSAIDs

2. How Amace 100mg tablet works? 

Being an NSAID, this drug works by inhibiting cyclooxygenase (COX) enzymes, both COX-1 and COX-2. However, it is moderately COX-2 selective. This leads to decrease in synthesis of prostaglandins, responsible for pain, swelling and fever.  The effect that takes to show may vary individually.

3. Indications of Amace 100mg Aceclofenac tablets

Amace provides pain relief in almost all painful conditions. Some of these are: rheumatoid arthritis, osteoarthritis and bursitis. Additionally, it also has uses in ankylosing spondylitis, post-operatively and after fractures and soft tissue injuries. This medicine has its regular uses also in toothache, dysmenorrhoea, renal colic. In traumatic conditions, this drug also reduces swelling.  

However, in very severe conditions, you may have to switch to parenteral form or steroids. 

4. How to use ?

You must take these tablets after your meal. Swallow this tablet in whole with an ample amount of water or any other fluid? Do not chew, crush or break this tablet.

5. Safety concerns in various situations

Do not take this Amace with alcohol. It may produce adverse reactions. Further, it may also precipitate heartburn that aggravates your condition. 

Pregnancy: Only animal studies are present in literature showing its side effects in pregnancy. We recommend you consult with your doctor before using Amace 100mg  in pregnancy.

Breastfeeding: Safety of Amace in breastfeeding is not available. Please consult your physician before use. 

Driving: Be cautious when you use this drug while driving. This may precipitate weakness after immediate intake. 

Kidney: If you have severe kidney disease, don’t take this drug. However, if you have mild kidney disease, your physician may modify the dose. 

Liver disease: In severe liver disease do not use Amace. However, no need to worry in simple liver derangements. Please consult your doctor about the dose modification in cases where liver functions are mildly deranged. 

What if you forget to take Amace 100mg Tablets? 

Take it as soon as possible if you forget at any instance. If you forget one day or two, take it the next time and continue taking it. We do not recommend doubling or tripling the dose in this context.

Superiority over other groups of NSAIDs 

The mechanism by which all NSAIDs work is similar. Considering potency there are several articles which you may want to read in specific medical literatures.

6. FAQs of Amace 100mg by Amtech

What is the use of Amace 100mg ?
It is a brand name of aceclofenac, which belongs to the class of NSAIDs. Amace works by decreasing the production of prostaglandins, the pain mediator. And, you can use this drug in all types of musculoskeletal, arthritic and traumatic pain.

What is the best time to take Amace 100mg tablets?
The best time is after your main meals. Take it within 10 minutes of intake of food. However, do not consume in empty stomach as it may lead to increased gastric acid production. And! it may lead to symptoms of heartburn and GERD. 

How long does it take for Amace to work?
Action starts within 15 minutes to half hour. This drug, after onset of action, will relieve your symptoms partially for 4-6 hours. However, to get complete relief from your symptoms, take this drug as per your prescription. 

Is Amace 100mg safe?
Yes, it is safe in most of the conditions. But dose adjustments are needed in liver and kidney diseases. Don’t use in pregnancy and lactation 

Can I take this drug if I am fasting? 

Yes, you can take Amace, if you are fasting or even! intermittent fasting.

Can I stop taking Amace 100mg if I feel better?

You can stop this drug after the prescription is over. Stoping it abruptly after few doses, may lead to recurrence of pain. However, you should not consume this drug beyond 15 days. Strictly! consult your physician if you have to do so.  

What if I overdose with Amace 100mg ?

Contact your health personnel immediately in this regard. Though there are no such systemic toxicity and antidotes for this drug, we request you be vigilant. 

Does this drug cause weight gain?

There are only a few reports that may cause weight gain while intaking this drug. So, consult your doctor for any weight gain concerns 

Can I take this drug with alcohol?

Alcohol doesn’t interfere in the mechanism of action of Amace 100mg. But it may increase acid production as a side effect. To prevent further worsening of your stomach, don’t take alcohol with this drug. We strictly prohibit use of alcohol with this drug.

Can I take antacids with Amace?

You can take antacids with this drug. But please take them at least two hours prior or after. 

Can I take PPIs with this drug? 

In most of the cases, your doctor will prescribe PPIs with this aceclofenac. You need to take PPIs one hour before meal and continue empty stomach for at least one hour before taking any food. 

What are the potential side effects of this tablet ?

These are epigastric pain, nausea, headache, dizziness amongst many. To prevent long term effects, this drug should not be used for more than 2 weeks in normal conditions. 

Is Amace 100mg injection available? 

At this moment, no preparations of aceclofenac are available in intravenous or intramuscular injection form in Nepal. 

Can I take Amace in COVID-19 infection ?

Yes, you can take this drug you have COVID infection. It helps in relieving all kinds of myalgia and other pains, which are some symptoms of the infection.

7. Quick tips: Amace 100mg

• Take this medicine after meals. 
• You can well tolerate this medicine. But, you must take in time and avoid certain things. 
• Avoid beverages, alcohol and smoking while taking Amace for best results.  
• Consult your doctor if you don’t see any effect for 2 weeks. 
• Don’t stop taking this medicine before consulting your doctor. 
• Call your doctor immediately if you develop severe pain abdomen, edema, decreased urination, severe vomiting and rashes
• Check for liver and renal function tests, if you need to take this drug for long time 

8. Summary: Amace 100mg

• Chemical Class: Dichlorobenzene
• Manufacturer: Amtech Med
• Available in combination: N/A
• Addiction: None   
• Bioavailability: 70%
• Metabolism: Liver 
• Excretion: Faeces, Urine 
• Therapeutic class: NSAIDs
• Price: Four Rupees for tablet 
• License Number:  6978
• Drug Type: Category B 
• Availability: In all pharmacies, Online pharmacies in Nepal
• Prescription Required? : Yes