Pansafe-40 pantoprazole tablets by Vega: 11 facts

Pansafe-40 pantoprazole tablet is an oral pantoprazole by Vega Pharmaceuticals. This company manufactures 90 products with a slogan ‘promising for better life’. The company has its headquarters at Anamnagar, Kathmandu. However, the production house is at Bungmati, Latitpur.

1. Introduction

Like other PPIs, Pansafe-40 pantoprazole acts by inhibiting H+/K+ ATPase in the parietal cells of your stomach. Pantoprazole is one of the most popular drugs in Nepal.

2.When to take Pansafe-40 pantoprazole ? 

Your physician may prescribe Pansafe on several occasions. The most common one is a pain abdomen due to peptic ulcers. You may have to take for a month or two for this condition. Your doctor may prescribe once or twice daily depending on the severity.

 Besides that, it may be a part of a triple regimen for treating Helicobacter pylori infection as well. It is also a choice in stress ulcers, bleeding ulcers, GERD and Zollinger Ellison syndrome. Doctors also use this drug for prophylaxis of aspiration pneumonia.

The usual dose is once daily, but it depends up to the severity of your illness

3.How to use Pansafe-40 pantoprazole tablets?

You must take this drug in an empty stomach at least one hour before the meal. Do not chew, crush or break this enteric coated tablet. If in case, you have to take twice, you must take it one hour before major meal in the evening. Don’t take any solid or liquid items during this one hour interval.

4. Side effects of Pansafe

Nausea, abdominal pain and dizziness may be present in 3-5%. Rarely rashes may appear as an adverse effect. Use of more than one year may lead to atrophic gastritis and hypergastrinemia. Long term use may also lead to osteoporosis and decrease in magnesium levels. Rare reports of gynaecomastia and erectile dysfunction can also be found in literature. Consult your doctor to clear any confusion about the side-effects of Pansafe-40 pantoprazole.

5.How does Pansafe work in your illness? 

In Peptic Ulcers 

Pansafe-40 pantoprazole works best for peptic ulcers when you take it once daily. You should take this drug at least one hour before the meal for the best results. The basis by which this great medicine works is by reducing the amount of gastric acid produced in your stomach. After you start this medicine, there is a decrease in the further growth of your ulcer. You may have to use other drugs alongside as well depending upon the severity. 

In Heartburn

Pansafe acts in this condition is similar to above conditions. By reducing the amount of hydrochloric acid, there is decrease in the mucosal irritation. This relieves pain and soothes your upper gastrointerstinal tract.

In Stress ulcers 

Taking Pansafe-40 pantoprazole in stress ulcers reduces the amount of gastric acid. This will improve your conditions. Stress ulcers occur in various traumatic and non-traumatic conditions in your body. So, other medicines, proper rest and stress relief are equally important to allow your body heal.

In Gastroesophageal Reflux disease (GERD)

In GERD, there will be chronic reflux of gastric acid towards your esophagus. By reducing the amount of this acid, there will be a decrease in your symptoms like pain by virtue of Pansafe. However, this may take some weeks to manifest. Besides, taking this medicine, you must also make lifestyle changes. This includes taking ample amounts of water and losing weight Similarly, avoiding food at least 4-5 hours of bed will be synergistic to the drug’s effect.

6. Safety Concerns of Pansafe

Do not take this drug with alcohol. Pansafe-40 pantoprazole is safe in pregnancy. Considering lactation, contact your doctor before use. You can use this drug while driving. This drug is safe in kidney and liver diseases.

Pansafe-40 pantoprazole by Vega
7. FAQs about Pansafe-40 pantoprazole

What is the use of Pansafe? 

It is a brand name of a pantoprazole, which belongs to the class of proton pump inhibitors. It works by decreasing the production of gastric acid. It’s use are chiefly in peptic ulcer, GERD and heartburn. 

What is the best time to take Pansafe tablets? 

The best time is in the early morning, as soon as you get off the bed. If you have to take twice, take this drug at least one hour before your meal both in the morning and evening. Don’t take any fluids or solid meals during this period. 

How long does it take for work? 

Action of Pansafe-40 pantoprazole starts within one hour. But to get ample relief you will have to take this drug for at least 2-4 weeks. You may still have some symptoms during this time. 

Is Pansafe safe? 

Yes, it is safe in most of the conditions. We recommend talking to your doctor to get best results in this scenario. 

Can I take this drug if I am fasting? 

Yes, you can take Pansafe 40mg, if you are fasting or even intermittent fasting. 

Can I stop taking Pansafe-40 pantoprazole if I feel better? 

We don’t recommend this. If you stop taking this medicine abruptly, there may be a surge of acid production. This will worsen your condition. Consult your physician before stopping this drug

What if I overdose with Pansafe ? 

Contact your health personnel immediately in this regard. Though there are no such systemic toxicity and antidotes for this drug, we request you be vigilant. 

Does this drug cause weight gain? 

There are only a few reports that may cause weight gain while intaking this drug. So, consult your doctor for any weight gain concerns 

Can I take Pansafe with alcohol? 

Alcohol doesn’t interfere in the mechanism of action of this drug. But it may increase acid production as a side effect. To prevent further worsening of your stomach, don’t take alcohol with this drug. 

Can I take painkillers with Pansafe? 

Pansafe and other brands are frequently prescribed together with painkillers. NSAIDS are known to cause stress ulcers. Hence, we recommend taking this drug along with painkillers. The dose and duration remains the same as above. 

What other dietary changes should I make while taking Pansafe-40 pantoprazole? 

We recommend you take a lot of fibers, decrease excess oil and fat consumption. Refrain from caffeine and carbonated beverages.

Can I take antacids with Pansafe 40? 

You can take antacids with this drug. But please take them at least two hours prior or after. 

What are the potential side effects of this brand?

The potential side effects of all pantoprazole are nausea and vomiting. Additionally, there may be rashes, insomnia and abdominal pain. If you consume for more than one year, you may suffer from hypomagnesemia, peripheral neuritis and osteoporosis.

Is Pansafe-40 prantoprazole injection available?

At this moment, preparation is not available for injection or infusion . However, the company may have plans to launch the injection in near future.

Can I take Pansafe-40 pantoprazole in COVID-19 infection?

Yes, you can take Pansafe, if you have a recent COVID infection. You can also take if you have recovery from the viral infection. Pansafe reduces stress ulcers and will improve your gastric health. Additionally, you can contact your doctor for more clarification.

8. How to use Pansafe-40 pantoprazole tablets?

You must take this drug in an empty stomach at least one hour before the meal. Do not chew, crush or break this enteric coated tablet. If in case, you have to take twice, you must take it one hour before major meal in the evening. Don’t take any solid or liquid items during this one hour interval.

9. Quick tips for Pansafe-40 pantoprazole

  • Take this medicine in the morning. Avoid any food (solid or liquid), for at least one hour after intake. 
  • You can well tolerate this medicine. But, you must take in time and avoid certain things. 
  • Avoid beverages, alcohol and smoking while taking Pansafe 40mg  for best results.  
  • Consult your doctor if you don’t see any effect for 2 weeks. 
  • Don’t stop taking this medicine before consulting your doctor. 
  • Call your doctor immediately if you develop edema, decreased urination, severe vomiting and rashes

10.Summary of Pansafe-40

  • Chemical Class: Sulfinylbenzimidazole
  • Manufacturer: Vega Pharmaceuticals
  • Available in combination:
  • Addiction: None   
  • Bioavailability: 70-80%
  • Metabolism: Liver 
  • Excretion: Faeces, Urine 
  • Therapeutic class: Gastrointestinal 
  • Action class: PPI 
  • Price: Eight Rupees for tablet. One strip comes has 15 tablets and will cost NPR 120.
  • License Number: 
  • Drug Type: Category C 
  • Availability: In all pharmacies, Online pharmacies in Nepal
  • Prescription Required? : No for tablet

11. Alternatives to Pansafe

  1. Pantop 40mg by Asian Pharmaceuticals
  2. P-GUT-40mg by Madras
  3. Panorma 40mg by DJPL
  4. Panzol 40mg by National 
  5. Panta-fast by Arya
  6. Pantera by Biogain
  7. Petor by Magnus


Though medical professionals have written content on this website, you must take these for informational purposes only. We request to consult your physician before using any drug and supplements mentioned in this portal.

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