MCQ about versican

MCQ about versican

Versican is found in?

a.Nucleus pulposus

b. Inner Layer of annulus fibrosus

c. Outer layer of annulus fibrosus

d. End plate cartilages

e. Vertebral body

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The correct answer is ‘b’

Versican is a proteoglycan found in the inner layer of annulus fibrosus.  It is also known as chondroitin sulfate proteoglycan core protein 2 or chondroitin sulfate proteoglycan 2 (CSPG2).

The annulus fibrosus or the outer layer of intervertebral disc has two layers. The outer layer is rich in type I collagen fibres, decorin and biglycan. The inner layer  consists of spherical cells, resembling chondrocytes and are rich in collagen I, II and versican

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